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词汇 Thogotovirus
分类 英语词汇 英语翻译词典
释义

Thogotovirus

英语百科

Thogotovirus

Predicted structure of THOV glycoprotein (left) compared with GP64 of the baculovirus, Autographa californica multicapsid nucleopolyhedrovirus (right)
Electron micrograph showing endocytosis (arrows) of Bourbon virus (scale bar: 100 nm)
Phylogeny of selected orthomyxoviruses, based on the nucleocapsid protein (scale bar: amino acid substitutions per site)

Thogotovirus is a genus of enveloped RNA viruses, one of six genera in the virus family Orthomyxoviridae. Their single-stranded, negative-sense RNA genome has six or seven segments. Thogotoviruses are distinguished from most other orthomyxoviruses by being arboviruses – viruses that are transmitted by arthropods, in this case usually ticks. Thogotoviruses can replicate in both tick cells and vertebrate cells; one subtype has also been isolated from mosquitoes. A consequence of being transmitted by blood-sucking vectors is that the virus must spread systemically in the vertebrate host – unlike influenza viruses, which are transmitted by respiratory droplets and are usually confined to the respiratory system.

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