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词汇 Agomelatine
分类 英语词汇 英语翻译词典
释义

Agomelatine

中文百科

阿戈美拉汀

褪黑素(上)和阿戈美拉汀(下)的分子结构对比
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阿戈美拉汀(英语:Agomelatine (商品名:维度新(Valdoxan))是一种褪黑素受体激动剂类抗抑郁药,由法国施维雅(Servier)公司研制。阿戈美拉汀主要用来治疗重度抑郁症(MDD),并且证据指出阿戈美拉汀不会产生停药综合症和导致性功能障碍(对比SSRI、SNRI与三环类抗抑郁药)。 阿戈美拉汀对改善睡眠和认知也有积极的作用。

英语百科

Agomelatine 阿戈美拉汀

Melatonin (top) vs. agomelatine (bottom)
Agomelatine-synthesis:;[43] and structure-activity studies:[44][45]

Agomelatine (BAN, rINN; trade names Valdoxan, Melitor, Thymanax) is a melatonergic antidepressant developed by the pharmaceutical company Servier. It is marketed for the treatment of major depressive disorder, primarily for its relatively favorable side effect profile: it avoids the weight gain, sexual dysfunction, and severe withdrawal associated with the most commonly-used classes of antidepressants (SSRIs, SNRIs, tricyclics), while providing similar therapeutic benefit.

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