Setastine

Setastine (Loderix) is an antihistamine used to treat allergies and rhinitis.

Setastine acts as a highly selective H₁ receptor antagonist. It has no anticholinergic, antiadrenergic, or antiserotonergic effects.

Setastine penetrates the blood-brain-barrier only weakly, hence, it is not sedating or is only mildly so.