Vigabatrin
（重定向自Sabril）
![](/Images/godic/202502/08/Vigabatrin2DCSD.svg0752.png")
![](/Images/godic/202502/08/Vigabatrin_ball-and-stick0753.png")
![Crystal Structure (pdb:1OHW) showing vigabatrin binding to specific residues in the active site of GABA-T, based off experiments by Storici et al.[20]](/Images/godic/202502/08/page1-220px-Vigabatrin_Chimera.pdf0753.jpg")
![](/Images/godic/202502/08/page1-600px-Vigabatrin_MOA.pdf0753.jpg")
Vigabatrin, also known as gamma-vinyl-GABA, is an antiepileptic drug that inhibits the breakdown of γ-aminobutyric acid (GABA) by acting as a suicide inhibitor of GABA transaminase (GABA-T). It is a structural analog of GABA, but does not bind to GABA receptors. It is sold under the brand name Sabril.