Nucleic acid structure prediction
![S. cerevisiae tRNA-PHE structure space: the energies and structures were calculated using RNAsubopt and the structure distances computed using RNAdistance.](/Images/godic/202502/07/TRNA_structure_space4201.png")
Nucleic acid structure prediction is a computational method to determine nucleic acid secondary and tertiary structure from its sequence. Secondary structure can be predicted from a single or from several nucleic acid sequences. Tertiary structure can be predicted from the sequence, or by comparative modeling (when the structure of a homologous sequence is known).