全反式视黄醇脱氢酶 (NAD)（英语：all-trans-retinol dehydrogenase (NAD)，EC 1.1.1.105），是一种以NAD或NADP为受体、作用于供体CH-OH基团上的氧化还原酶。这种酶能催化以下酶促反应：

全反式视黄醇脱氢酶 (NAD)能以全反式视黄醇和全反式视黄醛为底物，且对NAD/NADH辅因子有很强的特异性。这种酶既能识别处于游离态的底物也能识别与视黄醇结合蛋白相结合时的底物，但对结合状态下的底物具有更高的亲和性。

In enzymology, a retinol dehydrogenase (RDH) (EC1.1.1.105) is an enzyme that catalyzes the chemical reaction

Sometimes, in addition to or along with NAD, NADP can act as a preferred cofactor in the reaction as well. The substrate of the enzyme can be all-trans- or -cis- retinol. There are at least over 20 different isolated enzymes with RDH activity to date. Thus, the two substrates of this enzyme are retinol and NAD, whereas its 3 products are retinal, NADH (or NADPH in the case where NADP is a cofactor), and H.