心理神经免疫学（Psychoneuroimmunology），又称心理内分泌神经免疫学（Psychoendoneuroimmunology），是涉及心理学、神经系统和免疫系统的研究结果的一门学科。这学科主要研究神经系统和免疫力的相互作用，以及心理健康和身体健康的相互影响。

Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.