Protease-activated receptor 2
![](/Images/godic/202502/04/PBB_GE_F2RL1_206429_at_tn3438.png")
![](/Images/godic/202502/04/PBB_GE_F2RL1_213506_at_tn3438.png")
Protease activated receptor 2 (PAR2) also known as coagulation factor II (thrombin) receptor-like 1 (F2RL1) or G-protein coupled receptor 11 (GPR11) is a protein that in humans is encoded by the F2RL1 gene. PAR2 modulates inflammatory responses and acts as a sensor for proteolytic enzymes generated during infection.