血小板衍生生长因子（Platelet-derived growth factor，PDGF）为一种生长因子，可以调控细胞的生长和分化，且在血管新生上扮演重要角色。未控制的血管新生常常导致癌症。在化学上PDGF为糖蛋白二聚体，且有A和B两种不同形式，可组合为AA、AB和BB等结构。

PDGF是一种有效的间充质细胞丝裂原，包含纤维母细胞、平滑肌、神经胶细胞。在小鼠和人类中，PDGF信号网络都包括四种配体：PDGFA 到 PDGFAD，与两个受体:PDGFRA和PDGFRB。所有PDGF都表达到胞外，并通过二硫键连接形成同元二聚体，但只有PDGFA和B可以形成有功能的异元二聚体。

Platelet-derived growth factor (PDGF) is one of the numerous growth factors, or proteins that regulate cell growth and division. In particular, it plays a significant role in blood vessel formation (angiogenesis), the growth of blood vessels from already-existing blood vessel tissue. Uncontrolled angiogenesis is a characteristic of cancer. In chemical terms, platelet-derived growth factor is a dimeric glycoprotein composed of two A (-AA) or two B (-BB) chains or a combination of the two (-AB).