Osmaniye is a city in the Çukurova region of Turkey, the capital of Osmaniye Province. Area 3,767 km². Population of Osmaniye city: 219,339. Osmaniye Province: 512,804 (2014). Osmaniye is at an elevation of 125 meters (410.1 feet).

Located on the eastern edge of the Çukurova plain in the foothills of the Nur Mountains, the gateway between Anatolia and the Middle East, Osmaniye is on the Silk Road, a place of strategic importance and has been a settlement for various civilizations including the Hittites, Persians and Romans.