Moosburg an der Isar is a town in the Landkreis Freising of Bavaria, Germany.

The oldest town between Regensburg and Italy, it lies on the river Isar at an altitude of 421 m (1381 ft). It has 17,275 inhabitants (2005) and covers an area of 44 km². It is easily reached by the A 92 autobahn and regional trains on the Munich–Regensburg line. Furthermore, it takes just 10 minutes to get to Munich airport.