Agranulocyte
（重定向自Mononuclear leucocyte）
![Monocyte under a light microscope (40x) from a peripheral blood smear surrounded by red blood cells.](/Images/godic/202501/28/Monocyte_no_vacuoles3922.JPG")
![Reference ranges for blood tests of white blood cells, comparing mononuclear leukocytes amount (shown in yellow) with other cells.](/Images/godic/202501/28/Reference_ranges_for_blood_tests_-_white_blood_cells3922.png")
Agranulocytes, also known as mononuclear leukocytes, are white blood cells with a one-lobed nucleus. They are characterized by the absence of granules in their cytoplasm, which distinguishes them from granulocytes. Normal hematologic blood values of MLs are about 35% of all white blood cells. The 2 types of agranulocytes in the blood circulation are lymphocytes and monocytes. A third type of agranulocyte, the macrophage, is formed in the tissue when monocytes leave the circulation and differentiate into macrophages.