梅萨比人（拉丁语：Messapii，英语：Messapians）是历史上印欧人的一个族群，生活在亚平宁半岛的东南部（今天的普利亚），使用梅萨比语。

关于梅萨比人的起源仍有争议，最普遍的理论是从伊利里亚渡海而来。

The Messapians or Messapii were an Indo-European people that inhabited, in historical times, the south-eastern peninsula or "heel" of Italy (Salento, modern Apulia), known variously in ancient times as Calabria, Messapia and Iapygia. Their chief towns were Uzentum (modern Ugento), Rudiae (modern Lecce), Brundisium (modern Brindisi) and Hyria. They spoke the Messapian language. They are often referred to as "the most southerly of the Iapygian tribes".