Alright, so with membranous glomerulonephritis, the basement membrane becomes damaged which causes nephrotic syndrome.

好，所以在膜性肾小球肾炎中，基底膜受损，可导致肾病综合征。

If it goes untreated or the treatment is not successful, then membranous glomerulonephritis can progress to chronic renal failure.

如不加以治疗或治疗不成功，那么膜性肾小球肾炎会进展成慢性肾衰竭。

Alright, quick recap—membranous glomerulonephritis is where immune complexes deposit in the GBM, causing a thickening of that GBM and a " spike and dome" appearance that leads to nephrotic syndrome.

好，快速回顾一下：在膜性肾小球肾炎中，免疫复合物沉积在肾小球基膜，引起肾小球基膜增厚和“钉状突起”，导致肾病综合征。

Membranous glomerulonephritis most commonly affects caucasian adults, and it can be primary, or idiopathic, meaning it's not quite clear why these complexes form, and this accounts for the vast majority of cases.

白种人最易患膜性肾小球肾炎，它可以是原发的，即特发性的，意味着免疫复合物形成的机理尚不明确；极大多数膜性肾小球肾炎病因属于这类。