Beta-secretase 1
（重定向自Memapsin）
![](/Images/godic/202501/26/Protein_BACE1_PDB_1fkn4532.png")
![](/Images/godic/202501/26/PBB_GE_BACE1_217904_s_at_tn4532.png")
![Processing of the amyloid precursor protein](/Images/godic/202501/26/APP_processing4532.png")
![](/Images/godic/202501/26/PDB_1fkn_EBI4532.jpg")
Beta-secretase 1 (BACE1), also known as beta-site amyloid precursor protein cleaving enzyme 1, beta-site APP cleaving enzyme 1, membrane-associated aspartic protease 2, memapsin-2, aspartyl protease 2, and ASP2, is an enzyme that in humans is encoded by the BACE1 gene.