CDP-choline pathway
![Structures and localization of the enzymes in the CDP-choline pathway.[1]:415](/Images/godic/202501/22/Enzymes_of_the_CDP-choline_pathway0309.jpg")
The CDP-choline pathway, first identified by Eugene Kennedy in 1956, is the predominant mechanism by which mammalian cells synthesize phosphatidylcholine (PC) for incorporation into membranes or lipid-derived signalling molecules. The CDP-choline pathway represents one half of what is known as the Kennedy pathway. The other half is the CDP-ethanolamine pathway which is responsible for the biosynthesis of the phospholipid product phosphatidylethanolamine (PE).