Gepirone

Gepirone (INN) (developmental code names BMY-13805, MJ-13805, ORG-13011, TGFK07AD; proposed brand names Ariza, Variza) or gepirone hydrochloride (USAN) is an antidepressant and anxiolytic drug of the azapirone group that has never been marketed. Like other azapirones, it acts as a selective partial agonist of the 5-HT_1A receptor. Gepirone was under development in the U.S. in an extended release form, but despite completing phase III clinical trials, it failed to pass the drug approval process. As a result, gepirone, despite already having brand names chosen, did not manage to reach the pharmaceutical market.