So oncogenes or mutated tumor suppressor genes allow cells to keep growing uncontrollably resulting into tumors.
因此,癌基因或突变的抑癌基因使细胞不受控制地增长,导致肿瘤发生。
Osmosis-肌骨
To balance out cell growth, there are other genes called tumor suppressor genes which promote apoptosis or cell death of mutated cells.
为平衡细胞生长,还有其它基因,称作抑癌基因,促进突变细胞的凋亡或细胞死亡。
Osmosis-心血管
And this is due to mutations in the TSC1 or TSC2 tumor suppressor genes, genes that usually suppress tumor growth, therefore a mutation leads to myocyte overgrowth.
But even though they are dividing, these polyps only become malignant - meaning they only invade nearby tissues if there are additional mutations in other tumor suppressor genes like the p53 gene or in proto-oncogenes like K-RAS.