Druon Antigoon is a Flemish folkloric character. He was a mythical giant who lived in Antwerp.

Guarding a bridge on the river Scheldt, he exacted a toll from those crossing the river. For those who refused, he severed one of their hands and threw it into the river. Eventually, Antigoon was slain by a young Roman soldier named Brabo, who cut off the giant's own hand and flung it into the river.