Concentric hypertrophy leading to diastolic failure can also be caused by aortic stenosis, which is a narrowing of the aortic valve opening, as well by hypertrophic cardiomyopathy, an abnormal ventricular wall thickening often from a genetic cause.

导致舒张性心衰的向心性肥大，也可能由主动脉瓣狭窄（即主动脉瓣开口变窄）造成，也可能由肥厚型心肌病（一种遗传性异常心室壁增厚）引起。