Comitán (Spanish   ) (formally: Comitán de Domínguez, for Belisario Domínguez) is the fourth-largest city in the Mexican state of Chiapas. It is the seat of government of the municipality of the same name.

It is located in the east-central part of Chiapas, near the border with Guatemala at 16°15′N 92°08′W / 16.25°N 92.13°W / 16.25; -92.13. The municipality has an area of 1,043.30 km² (402.82 sq mi). Its largest other community is the town of Villahermosa Yalumá.