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词汇 Codimal
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英语百科

Phenylpropanolamine

RS-Norephedrin
Ball-and-stick model of the phenylpropanolamine molecule


Metabolic pathways of amphetamine in humans

 
 

4-Hydroxyphenylacetone
Phenylacetone
Benzoic acid
Hippuric acid

Amphetamine 
Norephedrine

4-Hydroxyamphetamine
4-Hydroxynorephedrine

Para-Hydroxylation
Para-Hydroxylation
Para-Hydroxylation

Beta-Hydroxylation
Beta-Hydroxylation

OxidativeDeamination

Oxidation
GlycineConjugation


In humans, norephedrine occurs as a metabolite of amphetamine. The beta-hydroxylation of amphetamine is mediated by dopamine β-hydroxylase.
Space filling model of phenylpropanolamine

Phenylpropanolamine (BAN and INN; PPA, β-hydroxyamphetamine), also known as the stereoisomers (−)-norephedrine and norpseudoephedrine, is a psychoactive drug of the phenethylamine and amphetamine chemical classes which is used as a stimulant, decongestant, and anorectic agent. It is commonly used in prescription and over-the-counter cough and cold preparations. In veterinary medicine, it is used to control urinary incontinence in dogs under trade names Propalin and Proin.

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