Cobalt chelatase

Cobalt chelatase (EC6.6.1.2) is an enzyme that catalyzes the chemical reaction

The 4 substrates of this enzyme are ATP, hydrogenobyrinic acid a,c-diamide, Co, and H₂O, whereas its 4 products are ADP, phosphate, cob(II)yrinic acid a,c-diamide, and H.

The aerobic cobalt chelatase (aerobic cobalamin biosynthesis pathway) consists of three subunits, CobT, CobN (IPR003672) and CobS (IPR006537).