Clorotepine

Clorotepine (INN; brand names Clotepin, Clopiben), also known as octoclothepin or octoclothepine, is a very potent atypical antipsychotic and central depressant of the tricyclic series which was derived from perathiepin in 1965 and soon thereafter marketed in the Czech Republic by Spofa for the treatment of schizophrenic psychosis. It is known to have high affinity for the D₁, D₂, D₃, D₄, 5-HT_2A, 5-HT_2B, 5-HT_2C, 5-HT₆, 5-HT₇, α_1A-adrenergic, α_1B-adrenergic, α_1D-adrenergic, and H₁ receptors, where it has been it has been confirmed to act as an antagonist (or inverse agonist) at most sites (and likely is as such at all of them based on structure-activity relationships), and it also blocks the reuptake of norepinephrine via inhibition of the norepinephrine transporter. Due to its very potent activity at the D₂ receptor, along with tefludazine, clorotepine was used as the basis for developing a 3-dimensional (3D) pharmacophore for D₂ receptor antagonists.

词汇	Clorotepin
分类	英语词汇英语翻译词典
释义	Clorotepin 英语百科 Clorotepine Clorotepine (INN; brand names Clotepin, Clopiben), also known as octoclothepin or octoclothepine, is a very potent atypical antipsychotic and central depressant of the tricyclic series which was derived from perathiepin in 1965 and soon thereafter marketed in the Czech Republic by Spofa for the treatment of schizophrenic psychosis. It is known to have high affinity for the D₁, D₂, D₃, D₄, 5-HT_2A, 5-HT_2B, 5-HT_2C, 5-HT₆, 5-HT₇, α_1A-adrenergic, α_1B-adrenergic, α_1D-adrenergic, and H₁ receptors, where it has been it has been confirmed to act as an antagonist (or inverse agonist) at most sites (and likely is as such at all of them based on structure-activity relationships), and it also blocks the reuptake of norepinephrine via inhibition of the norepinephrine transporter. Due to its very potent activity at the D₂ receptor, along with tefludazine, clorotepine was used as the basis for developing a 3-dimensional (3D) pharmacophore for D₂ receptor antagonists.
随便看	debt ridden debtridden debts are rolling up debts converted into shares debt secured Debt securities debt securities market Debt security Debt service debtservice Debt service coverage Debt service coverage ratio debt service figure debt service fund debt service fund requirements debt service fund requirments debt service guarantee debt service obligation debt service obligations debt service payment debt service payments debt service rate Debt Service Ratio debt service requirement debt service requirements 如何把握散文的情感意蕴是什么意思歌剧茶花女情感表达是什么意思虎牙直播情书规则是什么意思为了这个家情感语录英文是什么意思一日钟情书包是什么意思未知这首歌表达了什么情感是什么意思老吵架伤害的情感语录图片是什么意思三角形情感表达是什么意思平面设计文章情感表达方法是什么意思小甜情感文案怎么写是什么意思小情书告白姿势是什么意思情书第三季3期上是什么意思富有爱国情感的散文诗是什么意思自豪的事情书信四年级作文是什么意思积极情感语录短句文案是什么意思送男朋友的生日礼物，第一次送男朋友啥礼物爸爸生日送什么，送爸爸什么礼物最实用送朋友什么生日礼物好，生日礼物买什么好 60岁生日送什么好，给60岁老人生日礼物送家长什么礼物好，给家长买什么礼物好女儿生日送什么礼物好，孩子生日送什么礼物好男生十八送什么礼物好，十大男生喜欢的礼物女孩成人礼送什么礼物好，女儿18成年礼物送什么结婚回礼送什么好，结婚回礼送什么大方男生过生日送什么礼物，送男生什么礼物好送大学女生什么礼物好，送给女生最好的礼物结婚送礼送什么好，结婚适合送的礼物女生送男生什么礼物，女生送男生礼物排行榜送爸爸什么生日礼物，60岁送爸爸什么礼物好乔迁之喜送什么礼物好，新房乔迁送什么礼物好 identity vs.role confusion Identity: Youth and Crisis ideological advertisement id instinct idiographic approach idiographic research idiot savant iion channel II-type spatial disorientation ill-defined problem illegal demand Illinois Test of Psycholinguistic Abilities, ITPA illness illness behavior illness press 宫姓龙凤胎宝宝最佳取名指南王姓女孩取名字大全？ 2021年热门黄姓男宝宝取名字大全推荐爸爸姓杨,妈妈姓陈,给孩子取名字？宝宝取名，杨姓大全张姓男孩取名字大全？史姓取名字大全 \| 特别好记的史姓起名方法分享虎年男孩子取名指南：超全李姓宝宝取名大全如何根据乔姓取名？用古诗词给乔姓取名的大全！王姓女孩取名字大全？男孩属猪的李姓取名字大全乔赵姓龙凤胎取名攻略，个性名字推荐大全陈姓女孩取名字大全集梁姓取名字大全？双胞胎男孩取名大全？