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词汇 Cefodizime
分类 英语词汇 英语翻译词典
释义

Cefodizime

中文百科

头孢地嗪

头孢地嗪是一种第三代头孢菌素,属于半合成的抗生素。其对β内酰胺酶稳定,对头孢菌素酶和青霉素酶极稳定,且有较长的生物学半衰期。头孢地嗪对革兰阳性菌、革兰阴性菌均有抗菌活性,临床主要用于治疗链球菌、肺炎球菌等敏感菌所致的肺炎、支气管炎、胆囊炎、尿路感染、妇科感染及败血症等。

英语百科

Cefodizime 头孢地嗪

Cefodizime is a 3rd generation cephalosporin antibiotic with broad spectrum activity against aerobic gram positive and gram negative bacteria. Clinically, it has been shown to be effective against upper and lower respiratory tract infections, urinary tract infections, and gonorrhea. Cefodizime is a bactericidal antibiotic that targets penicillin-binding proteins (PBPs) 1A/B, 2, and 3 resulting in the eventual death of the bacterial cell. In vivo experimental models of infection showed that bacterial clearance by this drug is at least as effective compared with other 3rd generation cephalosporins. It has similar adverse effect profile to other 3rd generation cephalosporins as well, mainly being limited to gastrointestinal or dermatological side effects.

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