Bonifay is a city in Holmes County, Florida, United States. Bonifay was given its name from a prominent family that had a brick making factory in Pensacola, Florida. Frank Bonifay, the man behind the town's name, bought a stake in the L&N, now CSX, Railroad. As W. D. Chipley connected the rural Florida Panhandle, along the way he came up with names for certain communities the railroad bisected. The population was 4,078 at the 2000 census. According to the 2010 U.S Census the population had diminished to 2,793 people. It is the county seat of Holmes County.