Autoagglutination

Autoagglutination represents clumping of an individual's red blood cells (RBCs or erythrocytes) by his or her own serum due to the RBCs being coated on their surface by antibodies.

Autoagglutination is seen to occur in a type of immune mediated hemolytic anemia known as “cold antibody hemolytic anemia”. Here, the antibodies which act on the erythrocytes are active at temperatures below 30 degree C.