August Paul von Wassermann (21 February 1866 – 16 March 1925) was a German bacteriologist and hygienist.

Born in Bamberg, with Jewish origins, he studied at several universities throughout Germany, receiving his medical doctorate in 1888 from the University of Strassburg. In 1890 began work under Robert Koch at the Institute for Infectious Diseases in Berlin. In 1906 he became director of the division for experimental therapy and serum research at the institute, followed by a directorship of the department of experimental therapy at the Kaiser-Wilhelm-Gesellschaft for the Advancement of Science in Berlin-Dahlem (1913).