阿西斯（葡萄牙语：Assis）是巴西圣保罗州的一个市镇。总面积461.705平方公里，总人口98715人，人口密度213.8人/平方公里。

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Assis is a city and a municipality in the southwestern part of the state of São Paulo in Brazil. The population is 101,597 (2015 est.) in an area of 460.61 km². The town was founded on July 5, 1905 and became a municipality in 1917, when it was separated from Platina. It is the largest city of its microregion, and the 2nd of its mesoregion, and is 434 km away from the capital, São Paulo. The town has an annual average temperature of 21,37 °C, annual rainfall 1,441 mm (56.7 in), and the vegetation predominates Mata Atlântica and Cerrado, is then a transition zone of vegetation. Its Human Development Index (HDI) is 0.805, considered high if comparated to state and is in 28th place among Brazilian cities.