Anti-lymphocyte globulin

Anti-lymphocyte globulin (ALG) is an infusion of animal- antibodies against human T cells which is used in the treatment of acute rejection in organ transplantation. It was developed in the 1960s, during which time 74 scientific papers were published on its use. Experimental preparations were first used in the Stanford laboratories in heart transplantation, and commercial preparations have been available since the 1970s.