Andrographolide

Andrographolide is a labdane diterpenoid that has been isolated from the stem and leaves of Andrographis paniculata. Andrographolide is an extremely bitter substance.

Andrographolide has been studied for its effects on cell signaling, immunomodulation, and stroke. Study has shown that andrographlide may bind to a spectrum of protein targets including NF-κB and actin by covalent modification.