Over time, amylin builds up and aggregates in the islets.
久而久之,胰淀素堆积,并在胰岛里聚集。
Scishow 精选系列
At the same time, your pancreas secretes less insulin, which regulates blood sugar, and amylin, which signals fullness.
同时,胰腺减少分泌可调节血糖的胰岛素和可提示饱腹的胰淀素。
Scishow 精选系列
So when you cut calories, ghrelin levels rise and insulin and amylin levels plummet, signalling your brain to increase appetite—making you feel ravenous.
Now, along with insulin, beta cells also secrete islet amyloid polypeptide, or amylin, so while beta cells are cranking out insulin they also secrete an increased amount of amylin.
Amylin, or islet amyloid polypeptide (IAPP), is a 37-residue peptide hormone. It is cosecreted with insulin from the pancreatic β-cells in the ratio of approximately 100:1. Amylin plays a role in glycemic regulation by slowing gastric emptying and promoting satiety, thereby preventing post-prandial spikes in blood glucose levels.