唑尼沙胺（英语：Zonisamide）是一种磺胺类抗惊厥药，被批准用于辅助治疗成人的癫痫发作，婴儿的韦斯特综合症，伦诺克斯-加斯托二氏综合征、肌阵挛和全身强直－阵挛性发作。

Zonisamide is a sulfonamide anticonvulsant approved for use as an adjunctive therapy in adults with partial-onset seizures; infantile spasm, mixed seizure types of Lennox–Gastaut syndrome, myoclonic, and generalized tonic clonic seizure.