When the interdependent relationships between substances, between functions as well as between substances and functions get abnormal, life activities will be broken, thus bringing about dissociation of yin and yang, depletion of essence, and even an end of life.

当物质之间、功能之间以及物质与功能之间的相互依存关系异常时， 生命活动就会被打破， 从而导致阴阳离决、精气乃决， 甚至生命的终结。