CONCLUSION: Base pair substitution mutation and frame shift mutation were caused by folpet in Ames test.And DNA breakage in human PMNC might be induced by folpet.
灭菌丹可引起鼠伤寒沙门氏菌碱基置换和移码突变,并可能损伤人外周血淋巴细胞DNA的完整性。
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词汇 | Ames test |
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释义 |
Ames test
英语例句库
CONCLUSION: Base pair substitution mutation and frame shift mutation were caused by folpet in Ames test.And DNA breakage in human PMNC might be induced by folpet. 灭菌丹可引起鼠伤寒沙门氏菌碱基置换和移码突变,并可能损伤人外周血淋巴细胞DNA的完整性。
中文百科
艾美氏试验艾美氏试验(英语:Ames test,又称为细菌回复突变试验或安姆氏突变试验)为美国人布鲁斯·埃姆斯博士于1983年所提出的突变物测试方法。此法检测出175已知之致癌物,并发现其中有超过90%者皆显示为阳性(具突变性),因此,艾美氏试验也被做为先期测试方法之一。而现在正以艾美氏试验为模式系统,进行各式化学物可能的毒性及致突变性之安全评估,但仍需其它的测试辅助测试而进一步确认。
英语百科
Ames test 艾美氏试验![]() ![]() The Ames test is a widely employed method that uses bacteria to test whether a given chemical can cause mutations in the DNA of the test organism. More formally, it is a biological assay to assess the mutagenic potential of chemical compounds. A positive test indicates that the chemical is mutagenic and therefore may act as a carcinogen, because cancer is often linked to mutation. The test serves as a quick and convenient assay to estimate the carcinogenic potential of a compound because standard carcinogen assays on mice and rats are time-consuming (taking two to three years to complete) and expensive. However, false-positives and false-negatives are known. |
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