美国商会（United States Chamber of Commerce，简称：USCC）是一个代表多间企业和贸易协会的美国游说团体。美国商会并不是美国政府的官方单位。

美国商会由多位政策专家、游说家和律师组成。在政治方面。美国商会一般被认为属于保守主义团体。美国商会通常支持共和党候选人，但也有时会支持保守派的民主党候选人。美国商会是美国最大的游说团体之一，每年的开销金额超越了其他的游说团体。

The United States Chamber of Commerce (USCC) is a business-oriented American lobbying group. It is not an agency of the United States government.

Politically, the Chamber is generally considered to be a conservative organization. It usually supports Republican political candidates, though it has occasionally supported conservative Democrats. The Chamber is the largest lobbying group in the U.S., spending more money than any other lobbying organization on a yearly basis.