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词汇 Williamson synthesis
分类 英语词汇 英语翻译词典
释义

Williamson synthesis

英语百科

Williamson ether synthesis

Ether synthesis by reaction of salicylaldehyde with chloroacetic acid and sodium hydroxide[1]

The Williamson ether synthesis is an organic reaction, forming an ether from an organohalide and an a deprotonated alcohol (alkoxide). This reaction was developed by Alexander Williamson in 1850. Typically it involves the reaction of an alkoxide ion with a primary alkyl halide via an SN2 reaction. This reaction is important in the history of organic chemistry because it helped prove the structure of ethers.

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