Speedball (drug)

Speedball (also referred to as powerballing) is a term commonly referring to the intravenous use of cocaine with heroin or morphine in the same syringe. Some also use it with two syringes, one in each arm. The speedball can also be taken by insufflation. The original speedball used cocaine hydrochloride mixed with morphine sulfate, as opposed to heroin. The term can also be applied to use of pharmaceutical opioids, benzodiazepines or barbiturates along with stimulants. This cocktail of drugs can cause a strong physical dependence and withdrawal symptoms.