Verocytotoxin
Verocytotoxin is a Shiga-like toxin produced by the E. coli strain O157, and Shigella type 1.
It causes acute renal failure in children, as a result of Haemolytic uraemic syndrome.
The toxin has two parts. The A part damages gut epithelium through inhibiting its protein synthesis, facilitating entry to the blood stream. The 5 B parts are adapted to inserting the A part into epithelial cells.