There are already drugs that inhibit the cancer-causing form of ALK, which means that ALK is what scientists call a druggable target.

目前已有药物可以抑制ALK的致癌形式，这意味着ALK是科学家所称的“药物靶点”。

There are already drugs that inhibit the cancer-causing form of ALK, which means that ALK is what scientists call a druggable target.

已经有药物可以抑制 ALK 的致癌形式，这意味着 ALK 是科学家所说的药物靶点。

" We found that ALK acts in our brains and what it does: it allows our body to burn more calories per same food we eat."

“我们发现ALK在我们大脑中起作用，让我们的身体在吃同样的食物时能燃烧更多卡路里。”

So both an MYCN amplification or ALK gene fusion, where the oncogene is " turned on, " or a PHOX2B and chromosome 1 and 11 deletions, where tumor suppressor genes are " turned off, " can potentially cause uncontrolled cell growth.

因此，MYCN基因扩增或ALK基因的融合，即致癌基因被激活，或PHOX2B与1号、11号染色体缺失，即抑癌基因的失活，都可能导致细胞生长不受控制。