Treatment of hyperaldosteronism is usually with potassium-sparing diuretics, especially spironolactone, which competitively binds to aldosterone receptors on the principal and alpha-intercalated cells.

醛固酮增多症的治疗通常使用保钾利尿剂，尤其是螺内酯：其可竞争性结合主细胞及α-闰细胞上的醛固酮受体。