缩硫酮是缩酮的硫类似物，由酮与硫醇缩合而得。复杂的缩硫酮也可从Corey-Seebach反应合成。反应很容易进行，乙二硫醇室温就可与酮起反应。反应可用于羰基的保护，但缩硫酮比缩酮稳定得多。缩硫酮也可用催化氢化的方法还原为亚甲基。缩硫酮/缩硫醛具有特殊的极性翻转性质，原羰基碳变为亲核性，可用于合成。

In chemistry, a thioketal is the sulfur analogue of a ketal, with one of the oxygen replaced by sulfur. A dithioketal has both oxygens replaced by sulfur.

Thioketals can be obtained by reacting ketones or aldehydes with thioles.

Ketones can be reduced at neutral pH using the thioketal method. The thioketal prepared from the ketone can be easily reduced by catalytic hydrogenation using Raney nickel in a reaction known as the Mozingo reduction.