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词汇 Tandem duplication
分类 英语词汇 英语翻译词典
释义

Tandem duplication

英语百科

Gene duplication

Schematic of a region of a chromosome before and after a duplication event
Evolutionary fate of duplicate genes

Gene duplication (or chromosomal duplication or gene amplification) is a major mechanism through which new genetic material is generated during molecular evolution. It can be defined as any duplication of a region of DNA that contains a gene. Gene duplications can arise as products of several types of errors in DNA replication and repair machinery as well as through fortuitous capture by selfish genetic elements. Common sources of gene duplications include ectopic homologous recombination, retrotransposition event, aneuploidy, polyploidy, and replication slippage.

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