圣多美（葡萄牙语：São Tomé）是非洲岛国圣多美和普林西比的首都和最大城市，在圣多美岛上，2005年人口为56,166。

农贸市场

林业道路

渔港区

São Tomé is the capital city of São Tomé and Príncipe and is by far the nation's largest town. Its name is Portuguese for "Saint Thomas". The population of its agglomeration is 56,945 (2008 est.).