Objective To investigate the synergistic analgesic action of rotundine combined with subthreshold dose of dolantin.

摘要目的观察罗通定与阈下剂量哌替啶合用后对哌替啶镇痛作用的影响。

Conclusion The combined administration of dolantin and rotundine has significant synergistic action of analgesia, with reduced dose of dolantin and decreased incidence of addiction.

结论罗通定与阈下剂量派替啶合用可以增强镇痛效果，从而减少派替啶的用量，降低其药物依赖的发生概率。