Febrile neutrophilic dermatosis
（重定向自Sweet syndrome）
![](/Images/godic/202502/14/Sweet-syndrome_skin0652.png")
![Pustular lesions with central necrosis on the left leg of a patient with Sweet's syndrome associated with Crohn's disease.](/Images/godic/202502/14/Sweet's_syndrome_Crohn's_disease0652.gif")
![Punch biopsy of a skin lesion showing neutrophilic infiltration in the dermis, with no evidence of vasculitis (same patient with Crohn's disease).](/Images/godic/202502/14/Sweet's_syndrome_pathology0652.jpg")
Sweet's syndrome (SS), or acute febrile neutrophilic dermatosis is a skin disease characterized by the sudden onset of fever, an elevated white blood cell count, and tender, red, well-demarcated papules and plaques that show dense infiltrates by neutrophil granulocytes on histologic examination.