All right, as a quick recap, Tay-Sachs disease is a lysosomal storage disease that results in a buildup of GM2 ganglioside in neurons of the central nervous system.

好，快速回顾下：Tay-Sachs病是一种溶酶体贮积病，能引起中枢神经系统神经元中GM2神经节苷脂贮积。