圣克罗伊县（St. Croix County, Wisconsin）是美国威斯康辛州西部的一个县，西隔圣克罗伊河与明尼苏达州相望。面积1,906平方公里。根据美国2000年人口普查，共有人口63,155。县治哈得逊。

成立于1840年，县名来自圣克罗伊河。

St. Croix County is a county in the U.S. state of Wisconsin. As of the 2010 census, the population was 84,345. Its county seat is Hudson. The county was created in 1840 (then in the Wisconsin Territory) and organized in 1849.

St. Croix County is part of the Minneapolis-St. Paul-Bloomington, MN-WI Metropolitan Statistical Area. Between 2000 and 2010, it was the fastest-growing county in Wisconsin.