Such sensitisation can arise when sustained pain signals permanently change a nerve's ion channels, making even mild sensations indistinguishable from painful ones.

当持续的疼痛信号永久性地改变神经的离子通道时， 就会出现这种敏化，甚至使轻微的感觉与疼痛的感觉难以区分。

That said, it also revealed the glaring need for more sensitisation around the subject, especially after a celeb tweet that read – 'Depression is a consequence of drug abuse'.

它也揭示了对这个主题进行更多宣传的明显需求，尤其是在名人推特上写着“ 抑郁症是药物滥用的结果” 之后。