保险箱（英语：safe deposit box，或称 safety deposit box），是一种保安设备，一般设于金库，或银行或邮局的内部。保险箱保存的不外乎贵重的宝石、贵金属、货币，或重要的文档，如遗嘱、物业契据。人们为了防盗、防火、防洪、防攻击，或基于各种因素，而不选择把它们置于家中。按照特定的协议，使用保险箱前，租用者须向银行缴付费用，而保险箱只可用专用钥匙、银行的主密钥、特有的签署，或者一个夹杂各种性质的密码开启。另外，一些银行使用人体辨识技术加强保安。

在小说作品中，保险箱多用作伏线，尤其是恐怖小说和推理小说。举例，在《达文西密码》、《卧底》和《神鬼认证》，有部分故事情节涉及保险箱的操控。

"Safe deposit" redirects here; not to be confused with Safedeposits in Scotland.

A safe deposit box, sometimes known as a safety deposit box, is an individually secured container, usually held within a larger safe or bank vault. Safe deposit boxes are generally located in banks, post offices or other institutions. Safe deposit boxes are used to store valuable possessions, such as gemstones, precious metals, currency, marketable securities, important documents such as wills, property deeds, and birth certificates, or computer data storage that need protection from theft, fire, flood, tampering, or other perils. In the United States, renting out a safe deposit box in a bank does not mean that the property is automatically insured. An individual should still purchase insurance for the safe deposit box in order to cover theft and natural disasters.